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TYRO3 monoclonal antibody

货号: MB21215

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21215

Product Name :TYRO3 monoclonal antibody

Swiss-Prot :Q06418

Host :Mouse

Reactivity :Human

Applications :WB

Background :TYRO3: Tyrosine-protein kinase, also known as BYK, Brt, Dtk, Sky. Entrez Protein: NP_006284. It belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :96.9kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BYK; Brt; Dtk; RSE; Sky; Tif

Immunogen :Purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using TYRO3 mouse mAb against extracellular domain of human TYRO3 (aa41-429).

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）