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FGR monoclonal antibody

货号: MB21201

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21201

Product Name :FGR monoclonal antibody

Swiss-Prot :P09769

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :56kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SRC2; c-fgr; c-src2; p55c-fgr; p58c-fgr

Immunogen :Purified recombinant fragment of human FGR expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using FGR mouse mAb against HL60 (1) Raw264.7 (2) cell lysate.

Immunohistochemical analysis of paraffin-embedded human Spleen tissues using FGR mouse mAb

免疫沉淀（IP）

免疫组织化学（IHC）