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ESR1 monoclonal antibody

货号: MB21187

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21187

Product Name :ESR1 monoclonal antibody

Swiss-Prot :P03372

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1/500 - 1/2000

Background :ESR1: estrogen receptor 1. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ER; ESR; Era; ESRA; NR3A1

Immunogen :Synthetic peptide corresponding to aa(SLQKYYITGEAEGFPATVc) of human ESR1, conjugated to KLH.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ESR1 mouse mAb against MCF-7 cell lysate (1)