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CD20 monoclonal antibody

货号: MB21136

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21136

Product Name :CD20 monoclonal antibody

Swiss-Prot :P11836

Host :Mouse

Reactivity :Human

Applications :IHC,IF

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000

Background :CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1

Immunogen :Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using CD20 mouse mAb.