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RUNX-2 (D198) polyclonal antibody

货号: BS8734

价格：

一口价 ：￥ 800

货期：现货（1-2个工作日）

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No. :BS8734

Product Name :RUNX-2 (D198) polyclonal antibody

Swiss-Prot :Q13950

Host :Rabbit

Reactivity :Human, Mouse ,Rat, Chicken

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:200

Background :RUNX2 (Runt-related transcription Factor) is a transcription factor that binds to its canonical consensus sequence 5’- PYGPYGGT-3’ in a number of promoters and enhancers. They include LCK, T-cell receptor enhancers, and various bone related genes such as osteocalcin, osteopontin, and bone sialoprotein. As a result of this, RUNX2 is involved in osteoblastic differentiation and skeletal morphogenesis. RUNX2 contains a proline/serine/ threonine-rich region at its C-terminus that has shown to be critical for its transcriptional activity.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RUNX-2 (D198) polyclonal antibody detects endogenous levels of RUNX-2 protein.

BiowMW :57kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :460

促销价格2 :800

Alternative Name :Runt-related transcription factor 2; Acute myeloid leukemia 3 protein; Core-binding factor subunit alpha-1; CBF-alpha-1; Oncogene AML-3; Osteoblast-specific transcription factor 2; OSF-2; Polyomavirus enhancer-binding protein 2 alpha A subunit; PEA2-alpha A; PEBP2-alpha A; SL3-3 enhancer factor 1 alpha A subunit; SL3/AKV core-binding factor alpha A subunit; RUNX2; AML3; CBFA1; OSF2; PEBP2A

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RUNX2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of RUNX2 expression in HEK293T (A), DLD (B), mouse spleen (C) whole cell lysates.

Immunohistochemical analysis of RUNX2 staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of RUNX2 staining in B12 cells.

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