Product Name :MBNL2 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :IHC,1:100 - 1:500|IF/ICC,1:100 - 1:500
Background :This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :MBNL2 polyclonal antibody detects endogenous levels of MBNL2 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MBNL2;MBLL;MBLL39;PRO2032
Immunogen :KLH conjugated synthetic peptide derived from human MBNL2 : 101-200/373
Modification :Unmodification