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alpha 1 Spectrin polyclonal antibody

货号: BS71767

价格：

一口价 ：￥ 800

货期：现货（1-2个工作日）

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No. :BS71767

Product Name :alpha 1 Spectrin polyclonal antibody

Swiss-Prot :P02549

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :alpha 1 Spectrin polyclonal antibody detects endogenous levels of alpha 1 Spectrin protein.

BiowMW :300kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :460

促销价格2 :800

Alternative Name :SPTA1;EL2;HPP;HS3;SPH3;SPTA

Immunogen :Recombinant full length protein of human alpha 1 Spectrin.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of alpha 1 Spectrin expression in A549 (A), mouse liver (B), mouse lung (C), rat heart (D) whole cell lysates.

Immunohistochemical analysis of alpha 1 Spectrin staining in human tonsil formalin fixed paraffin embedded tissue section.