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VE Cadherin polyclonal antibody

货号: BS70310

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS70310

Product Name :VE Cadherin polyclonal antibody

Swiss-Prot :P33151

Host :Rabbit

Reactivity :Human, Mouse, Rat, Chicken

Applications :WB IHC

Application_all :WB 1:500 - 1:1000 IHC 1:50 - 1:200

Background :This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :VE Cadherin polyclonal Antibody detects endogenous levels of VE Cadherin protein.

BiowMW :~ 98, 140 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human VE Cadherin.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of VE Cadherin expression in A375 (A), U87MG (B), mouse brain (C), rat brain (D) whole cell lysates.

Immunohistochemical analysis of VE Cadherin staining in human brain formalin fixed paraffin embedded tissue section.

Qimai Feiluoping Decoction Inhibits EndMT to Alleviate Pulmonary Fibrosis by Reducing PI3K/AKT/mTOR Pathway-Mediated the Restoration of Autophagy

JournalJournal of Inflammation Research

ApplicationWB

IF4.1

SpeciesHuman,Mouse

PMID40589610