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HDAC9 polyclonal antibody

货号: BS6831

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS6831

Product Name :HDAC9 polyclonal antibody

Swiss-Prot :Q9UKV0

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:100 - 1:500

Background :Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HDAC9 polyclonal antibody detects endogenous levels of HDAC9 protein.

BiowMW :110KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Histone deacetylase 9; HD9; Histone deacetylase 7B; HD7; HD7b; Histone deacetylase-related protein; MEF2-interacting transcription repressor MITR; HDAC9; HDAC7; HDAC7B; HDRP; KIAA0744; MITR

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human HDAC9.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of HDAC9 expression in LO2 (A), mouse heart (B), rat heart (C), Ramos (D) whole cell lysates.

Immunohistochemical analysis of HDAC9 staining in human lung cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of HDAC9 staining in Ramos cells.