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LXRα polyclonal antibody

货号: BS6785

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS6785

Product Name :LXRα polyclonal antibody

Swiss-Prot :Q13133

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB,1:500 - 1:1000

Background :The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LXRα polyclonal antibody detects endogenous levels of LXRα protein.

BiowMW :50KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LXRA; Oxysterols receptor LXR-alpha; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LXRα.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LXRα expression in SHSY5Y (A), HEK293T (B), NIH3T3 (C), rat muscle (D) whole cell lysates.

Pomegranate peel polyphenols inhibit lipid accumulation and enhance cholesterol efflux in raw264.7 macrophages

JournalFood & Function

ApplicationWB

IF5.396

SpeciesHuman

PMID27334099
Pomegranate punicalagin inhibits the foam cells formation in Raw264.7 macrophages

JournalFood Science and Technology

ApplicationWB

IF2.602

SpeciesMouse

PMID