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PON2 polyclonal antibody

货号: BS6697

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS6697

Product Name :PON2 polyclonal antibody

Swiss-Prot :Q15165

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PON2 polyclonal antibody detects endogenous levels of PON2 protein.

BiowMW :37kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Serum paraoxonase/arylesterase 2; PON 2; Aromatic esterase 2; A-esterase 2; Serum aryldialkylphosphatase 2

Immunogen :Recombinant fusion protein of human PON2(NP_000296.2).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PON2 expression in HepG2 (A), HEK293T (B) whole cell lysates.

A highly selective marker reaction for measuring the activity of human carboxylesterase 1 in complex biological samples

JournalRSC Advances

ApplicationWB

IF3.361

SpeciesHuman

PMID