产品类别

联系我们

电话:18013895086

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

TrkB polyclonal antibody

货号: BS6683

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6683

Product Name :TrkB polyclonal antibody

Swiss-Prot :Q16620

Host :Rabbit

Reactivity :Human, Mouse, Rat, Bovine, Chicken, Dog, Monkey, Rabbit

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TrkB polyclonal antibody detects endogenous levels of TrkB protein.

BiowMW :130KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TrkB.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of TrkB expression in rat heart (A), mouse kidney (B) whole cell lysates.

Immunohistochemical analysis of TrkB staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of TrkB staining in HL60 cells.

Sigma 1 receptor activation regulates brain-derived neurotrophic factor through NR2A-CaMKIV-TORC1 pathway to rescue the impairment of learning and memory induced by brain ischaemia/reperfusion

JournalPsychopharmacology

ApplicationWB

IF3.13

SpeciesMouse

PMID25420607