Product Name :Inhibin beta B polyclonal antibody
Reactivity :Human, Mouse, Rat, Bovine, Chicken, Pig, Sheep, Zebrafish
Application_all :WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200
Background :Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Activin B is a dimer of alpha and beta-B that plays a role in several essential biological processes including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and wound healing.
Inhibin B is a dimer of alpha and beta-B that plays a crucial role in the regulation of the reproductive system by inhibiting the secretion of follicle-stimulating hormone (FSH) from the anterior pituitary gland. Thereby, maintains reproductive homeostasis in both males and females. Acts as a more potent suppressor of FSH release than inhibin A (By similarity).
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Inhibin beta B polyclonal antibody detects endogenous levels of Inhibin beta B protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :INHBB; Inhibin beta B chain; Activin beta-B chain
Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Inhibin beta B.
Modification :Unmodification
