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BAP1 polyclonal antibody

货号: BS6450

价格：

一口价 ：￥ 800

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS6450

Product Name :BAP1 polyclonal antibody

Swiss-Prot :Q92560

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :BAP1 polyclonal antibody detects endogenous levels of BAP1 protein.

BiowMW :80KDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :460

促销价格2 :800

Alternative Name :BAP1;HUCEP-13;UCHL2;hucep-6

Immunogen :Recombinant full length protein of human BAP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of BAP1 expression in HL60 (A), THP1 (B), mouse kidney (C), rat brain (D) whole cell lysates.

Immunohistochemical analysis of BAP1 staining in human breast cancer formalin fixed paraffin embedded tissue section.