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KRAS polyclonal antibody

货号: BS6231

价格：

一口价 ：￥ 800

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6231

Product Name :KRAS polyclonal antibody

Swiss-Prot :P01116

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:200

Background :This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :KRAS polyclonal antibody detects endogenous levels of KRAS protein.

BiowMW :21KDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :460

促销价格2 :800

Alternative Name :KRAS;C-K-RAS;CFC2;K-RAS2A;K-RAS2B;K-RAS4A;K-RAS4B;KI-RAS;KRAS1;KRAS2;NS;NS3;RALD;RASK2;c-Ki-ras2

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human KRAS.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of KRAS expression in H446 (A), mouse kidney (B), mouse testis (C), rat kidney (D) whole cell lysates.

Immunohistochemical analysis of KRAS staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of KRAS staining in MCF7 cells.

FOXC2 promotes colorectal cancer metastasis by directly targeting MET

JournalOncogene

ApplicationWB

IF7.971

SpeciesHuman

PMID25381815
miR-134 Functions as a Tumor Suppressor in Cell Proliferation and Epithelial-to-Mesenchymal Transition by Targeting KRAS in Renal Cell Carcinoma Cells

JournalDna And Cell Biology

ApplicationWB

IF3.191

SpeciesHuman

PMID25811077
Targeting oncogenic K-RAS mutants with small-molecule degrader XMU-MP-9 through NEDD4-1

JournalActa Pharmaceutica Sinica B

ApplicationWB

IF14.6

SpeciesHuman

PMID