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IFN beta polyclonal antibody

货号: BS62219

价格：

一口价 ：￥ 800

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS62219

Product Name :IFN beta polyclonal antibody

Swiss-Prot :P01574

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IFN beta polyclonal antibody detects endogenous levels of IFN beta protein.

BiowMW :22kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :460

促销价格2 :800

Alternative Name :Interferon beta; Interferon β; IFN-beta; IFN-β; IFNβ; Fibroblast interferon; IFB; IFNB

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IFN beta.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of IFN beta expression in Hela (A), H1688 (B), H446 (C), mouse lung (D), mouse kidney (E), rat spleen (F) whole cell lysates.

Immunohistochemical analysis of IFN beta staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of IFN beta staining in A549 cells.

Respiratory Syncytial Virus Infection Upregulates NLRC5 and Major Histocompatibility Complex Class I Expression through RIG-I Induction in Airway Epithelial Cells

JournalJournal Of Virology

ApplicationWB

IF4.501

SpeciesHuman

PMID25972545