Product Name :SUMO4 Recombinant Rabbit mAb
Reactivity :Human, Mouse, Rat
Applications :WB,ICC/IF,FC,IP
Application_all :WB: 1:1000-1:10000; ICC/IF: 1:200-1:500; FC: 1:100-1:1000; IP: 1:20-1:50
Background :This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq, Jul 2008]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :IDDM5; SMT3H4; SUMO-4; dJ281H8.4
Immunogen :A synthetic peptide of human SUMO4
Modification :Unmodification