Product Name :NF-kB p65 Recombinant Rabbit mAb
Application_all :WB: 1:1000-1:5000; IP: 1:20-1:100
Background :Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of Schwann cell differentiation; positive regulation of miRNA transcription; and response to ischemia. Located in chromatin; cytoplasm; and nucleus. Part of protein-containing complex. Is active in synapse. Used to study Parkinsonism; encephalitis; status epilepticus; and steatotic liver disease. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); colitis; end stage renal disease; and liver disease (multiple). Human ortholog(s) of this gene implicated in ductal carcinoma in situ; lung non-small cell carcinoma; lymphoma; and renal cell carcinoma. Orthologous to human RELA (RELA proto-oncogene, NF-kB subunit). [provided by Alliance of Genome Resources, Jul 2025]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :NFkB; nos2
Immunogen :A synthetic peptide of Human NF-kB p65
Modification :Unmodification
