Product Name :IGF-I receptor beta Recombinant Rabbit mAb
Reactivity :Human, Mouse, Rat
Applications :WB,ICC/IF,FC,IP
Application_all :WB: 1:1000; ICC/IF: 1:200-1:1000; FC: 1:50-1:100; IP: 1:20-1:50
Background :This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :IGFR; CD221; IGFIR; JTK13; IGF1R
Immunogen :Recombinant protein of human IGF-I receptor beta
Modification :Unmodification
