Product Name :SV40 Large T Antigen Recombinant Rabbit mAb
Applications :WB,ICC/IF,FC,IP
Application_all :WB: 1:1000 ; ICC/IF: 1:50 ; FC: 1:200-1:500 ; IP: 1:20-1:50
Background :Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Large T antigen; LT; LT-AG
Immunogen :Recombinant protein SV40 Large T Antigen
Modification :Unmodification
