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Hamartin Recombinant Rabbit mAb

货号: BS48800

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

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No. :BS48800

Product Name :Hamartin Recombinant Rabbit mAb

Swiss-Prot :Q92574

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,FC,IP

Application_all :WB: 1:1000 ; IHC-P: 1:100-1:200 ; FC: 1:20 ; IP: 1:20-1:50

Background :This gene is a tumor suppressor gene that encodes the growth inhibitory protein hamartin. The encoded protein interacts with and stabilizes the GTPase activating protein tuberin. This hamartin-tuberin complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signalling which is a major regulator of anabolic cell growth. This protein also functions as a co-chaperone for Hsp90 that inhibits its ATPase activity. This protein functions as a facilitator of Hsp90-mediated folding of kinase and non-kinase clients, including Tsc2 and thereby preventing their ubiquitination and proteasomal degradation. Mutations in this gene have been associated with tuberous sclerosis. [provided by RefSeq, Apr 2018]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :150-170 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :LAM; TSC

Immunogen :A synthetic peptide of human Hamartin

Conjugate :Unconjugated