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PAX5 Recombinant Rabbit mAb

货号: BS48398

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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详细信息检测数据实验指南文献

No. :BS48398

Product Name :PAX5 Recombinant Rabbit mAb

Swiss-Prot :Q02548

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,ICC/IF,FC,IP

Application_all :WB: 1:1000-1:5000 ; IHC-P: 1:1000-1:5000 ; ICC/IF: 1:100-1:200 ; FC: 1:20-1:50 ; IP: 1:20

Background :This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :45 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :ALL3; BSAP

Immunogen :A synthetic peptide of human PAX5

Conjugate :Unconjugated