Product Name :p57 Kip2 Recombinant Rabbit mAb
Reactivity :Human,Mouse,Rat
Applications :WB,IHC-P,ICC/IF,FC,IP
Application_all :WB: 1:1000 ; IHC-P: 1:100-1:200 ; ICC/IF: 1:100-1:200 ; FC: 1:200-1:500 ; IP: 1:20-1:50
Background :This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BWS; WBS; p57; BWCR; KIP2; p57Kip2
Immunogen :A synthetic peptide of human p57 Kip2
Modification :Unmodification
