Product Name :ZAP70 Recombinant Rabbit mAb
Applications :WB,IHC-P,ICC/IF,IP
Application_all :WB: 1:2000-1:20000 ; IHC-P: 1:200-1:500 ; ICC/IF: 1:200-1:500 ; IP: 1:10-1:100
Background :This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
Immunogen :A synthetic peptide of human ZAP70
Modification :Unmodification
