Product Name :HuR/ELAVL1 Recombinant Rabbit mAb
Reactivity :Human,Mouse,Rat
Applications :WB,IHC-P,ICC/IF,FC,IP
Application_all :WB: 1:1000 ; IHC-P: 1:200-1:500 ; ICC/IF: 1:100-1:200 ; FC: 1:200-1:2000 ; IP: 1:20-1:50
Background :The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :HUR; Hua; MelG; ELAV1
Immunogen :A synthetic peptide of human HuR/ELAVL1
Modification :Unmodification
