Product Name :HP1 gamma Recombinant Rabbit mAb
Reactivity :Human,Mouse,Rat
Applications :WB,IHC-P,ICC/IF,FC
Application_all :WB: 1:1000 ; IHC-P: 1:100-1:200 ; ICC/IF: 1:100 ; FC: 1:50-1:100
Background :At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :HECH; HP1-GAMMA; HP1Hs-gamma
Immunogen :A synthetic peptide of mouse HP1 gamma
Modification :Unmodification
