Product Name :alpha Synuclein Recombinant Rabbit mAb
Applications :WB,IHC,ICC/IF,FC,IP
Application_all :WB: 1:1000-1:5000 ; IHC: 1:100-1:200 ; ICC/IF: 1:200-1:2000 ; FC: 1:200 ; IP: 1:500
Background :Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PD1; NACP; PARK1; PARK4
Immunogen :A synthetic peptide of human alpha Synuclein
Modification :Unmodification