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FADD Recombinant Rabbit mAb

货号: BS47233

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47233

Product Name :FADD Recombinant Rabbit mAb

Swiss-Prot :Q13158

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:1000-1:5000 ; IHC: 1:20-1:100 ; ICC/IF: 1:20-1:50 ; FC: 1:20 ; IP: 1:20-1:50

Background :The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :28 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :GIG3; MORT1

Immunogen :A synthetic peptide of human FADD

Conjugate :Unconjugated