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DNA Ligase IV Recombinant Rabbit mAb

货号: BS46997

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS46997

Product Name :DNA Ligase IV Recombinant Rabbit mAb

Swiss-Prot :P49917

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,ICC/IF

Application_all :WB: 1:1000 ; IHC-P: 1:50 ; ICC/IF: 1:100

Background :The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :104 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :LIG4S

Immunogen :Recombinant protein of human DNA Ligase IV

Conjugate :Unconjugated