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ORP150 Recombinant Rabbit mAb

货号: BS46480

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

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No. :BS46480

Product Name :ORP150 Recombinant Rabbit mAb

Swiss-Prot :Q9Y4L1

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:1000-1:5000 ; IHC: 1:50-1:200 ; ICC/IF: 1:50-1:200 ; FC: 1:20 ; IP: 1:20-1:50

Background :The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :150 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :Grp170; HSP12A; ORP150; GRP-170; ORP-150

Immunogen :A synthetic peptide of human ORP150

Conjugate :Unconjugated