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53BP1 Recombinant Rabbit mAb

货号: BS45676

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45676

Product Name :53BP1 Recombinant Rabbit mAb

Swiss-Prot :Q12888

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,ICC/IF

Application_all :WB: 1:5000-1:50000 ; IHC-P: 1:50-1:100 ; ICC/IF: 1:100-1:200

Background :This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :450 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :TP53; p202; 53BP1; TDRD30; p53BP1

Immunogen :A synthetic peptide of human 53BP1

Conjugate :Unconjugated