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CD31 Recombinant Rabbit mAb

货号: BS45621

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

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No. :BS45621

Product Name :CD31 Recombinant Rabbit mAb

Swiss-Prot :Q08481

Host :Rabbit

Reactivity :Mouse,Rat

Applications :WB,ICC/IF,IHC-P

Application_all :WB: 1:1000 ; ICC/IF: 1:100 ; IHC-P: 1:100-1:200

Background :Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore.

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :130-135 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :Cd31; Pecam; C85791; PECAM-1

Immunogen :Recombinant protein of mouse CD31

Conjugate :Unconjugated