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ROCK1 Recombinant Rabbit mAb

货号: BS45235

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS45235

Product Name :ROCK1 Recombinant Rabbit mAb

Swiss-Prot :Q13464

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,FC,IP

Application_all :WB: 1:1000 ; IHC-P: 1:200-1:1000 ; FC: 1:100 ; IP: 1:50-1:100

Background :This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :158 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :ROCK-I; P160ROCK

Immunogen :A synthetic peptide of human ROCK1

Conjugate :Unconjugated