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Securin Recombinant Rabbit mAb

货号: BS45220

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS45220

Product Name :Securin Recombinant Rabbit mAb

Swiss-Prot :O95997

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,ICC/IF,FC

Application_all :WB: 1:2000-1:20000 ; IHC-P: 1:100-1:200 ; ICC/IF: 1:50 ; FC: 1:20-1:50

Background :The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :25 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :EAP1; PTTG; HPTTG; TUTR1

Immunogen :A synthetic peptide of human Securin

Conjugate :Unconjugated