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USP13 Recombinant Rabbit mAb

货号: BS45151

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS45151

Product Name :USP13 Recombinant Rabbit mAb

Swiss-Prot :Q92995

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,ICC/IF,FC

Application_all :WB: 1:1000-1:5000 ; ICC/IF: 1:100 ; FC: 1:1000-1:10000

Background :Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD). Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13.

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :97 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :ISOT3; IsoT-3

Immunogen :A synthetic peptide of human USP13

Conjugate :Unconjugated