Product Name :Phospho-ERK1 (Thr202/Tyr204) / ERK2 (Thr185/Tyr187) Recombinant Rabbit mAb
Applications :WB,IHC-P,ICC/IF,FC
Application_all :WB: 1:1000-1:5000 ; IHC-P: 1:50 ; ICC/IF: 1:100-1:200 ; FC: 1:200-1:1000
Background :The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Thr202/Tyr204 of human Erk1
Modification :Phosphorylated
