Product Name :Phospho-160 kD Neurofilament Medium (Ser614/Ser619) Recombinant Rabbit mAb
Application_all :WB: 1:1000 ; IHC-P: 1:100-1:200
Background :Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :NFM; NEF3; NF-M
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Ser614/Ser619 of human 160 kD Neurofilament Medium
Modification :Phosphorylated
