Product Name :Phospho-BTK (Tyr551) Recombinant Rabbit mAb
Application_all :WB: 1:1000 ; ICC/IF: 1:200-1:500
Background :The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :AT; ATK; BPK; XLA; IMD1; AGMX1; IGHD3; PSCTK1
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Tyr551 of human BTK
Modification :Phosphorylated