Product Name :Phospho-PDGFR alpha (Tyr720) Recombinant Rabbit mAb
Reactivity :Human,Mouse,Rat
Applications :WB,ICC/IF,FC
Application_all :WB: 1:1000-1:5000 ; ICC/IF: 1:100 ; FC: 1:200-1:1000
Background :This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CD140A; PDGFR2; PDGFR-2
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Tyr720 of human PDGFR alpha
Modification :Phosphorylated
