Product Name :Phospho-CD3 zeta (Tyr83) Recombinant Rabbit mAb
Applications :WB,IHC,ICC/IF,FC,IP
Application_all :WB: 1:1000-1:5000 ; IHC: 1:100 ; ICC/IF: 1:100 ; FC: 1:20 ; IP: 1:20
Background :The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Tyr83 of human CD3 zeta
Modification :Phosphorylated
