Product Name :Phospho-p95 NBS1 (Ser343) Recombinant Rabbit mAb
Application_all :WB: 1:1000 ; ICC/IF: 1:50-1:100
Background :Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ATV; NBS; P95; NBS1; AT-V1; AT-V2
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Ser343 of human p95 NBS1
Modification :Phosphorylated
