Product Name :Phospho-BubR1 (Thr680) Recombinant Rabbit mAb
Applications :WB,ICC/IF,FC,IP
Application_all :WB: 1:1000 ; ICC/IF: 1:100 ; FC: 1:200-1:500 ; IP: 1:20-1:50
Background :This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Thr680 of human BubR1
Modification :Phosphorylated
