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Phospho-Pyruvate Dehydrogenase E1-alpha subunit (Ser293) Recombinant Rabbit mAb

货号: BS43266

价格：

一口价 ：￥ 880

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS43266

Product Name :Phospho-Pyruvate Dehydrogenase E1-alpha subunit (Ser293) Recombinant Rabbit mAb

Swiss-Prot :P08559

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,IP

Application_all :WB: 1:1000-1:5000 ; IHC-P: 1:100-1:200 ; IP: 1:10-1:100

Background :The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :The antibody detects endogenous levels of it

BiowMW :43 kDa

Note :For research use only, not for use in diagnostic procedure.

促销价格1 :508

促销价格2 :880

促销价格3 :1580

Alternative Name :PDHA; PDHAD; PHE1A; PDHCE1A

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser293 of human Pyruvate Dehydrogenase E1-alpha subunit

Conjugate :Unconjugated