Product Name :Phospho-GABA B Receptor 2 (Ser893) Recombinant Rabbit mAb
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:1000 ; IHC-P: 1:100-1:200
Background :This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :HDMX; hdm2; ACTFS
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Ser893 of human GABA B Receptor 2
Modification :Phosphorylated
