Product Name :Phospho-B MyB (Thr487) Recombinant Rabbit mAb
Applications :WB,IHC-P,ICC/IF,FC
Application_all :WB: 1:1000 ; IHC-P: 1:1000-1:5000 ; ICC/IF: 1:500-1:1000 ; FC: 1:200-1:1000
Background :The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BMYB; B-MYB
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Thr487 of human B MyB
Modification :Phosphorylated