Product Name :Phospho-Src (Tyr419) Recombinant Rabbit mAb
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:1000-1:5000 ; FC: 1:100
Background :This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ASV; SRC1; THC6; c-SRC; p60-Src
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Tyr419 of human Src
Modification :Phosphorylated
