Product Name :Phospho-TBK1 (Ser172) Recombinant Rabbit mAb
Application_all :WB: 1:1000-1:5000
Background :The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :NAK; T2K; FTDALS4
Immunogen :A synthetic phosphopeptide corresponding to residues surrounding
Ser172 of human TBK1
Modification :Phosphorylated
