Product Name :Acetyl-Histone H4 (Lys8) Recombinant Rabbit mAb
Reactivity :Human, Mouse, Rat
Applications :WB,IHC,ICC/IF,FC,IP
Application_all :WB: 1:2000-1:10000 ; IHC: 1:200-1:2000 ; ICC/IF: 1:200-1:500 ; FC: 1:20 ; IP: 1:20
Background :Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Product :1mg/ml in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :The antibody detects endogenous levels of it
Note :For research use only, not for use in diagnostic procedure.
Immunogen :A synthetic acetylpeptide corresponding to residues surrounding Lys8 of human Histone H4
Modification :Unmodification
