产品类别

联系我们

电话:18013895086

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Recombinant Dectin 1 Rabbit mAb

货号: BS37024

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS37024

Product Name :Recombinant Dectin 1 Rabbit mAb

Host :Rabbit

Reactivity :Mouse

Applications :WB, IHC, IF/ICC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/200)

Background :C-type lectin domain family 7 member A: Lectin that functions as a pattern recognizing receptor (PRR) specific for beta-1,3-linked and beta-1,6-linked glucans, which constitute cell wall constituents from pathogenic bacteria and fungi . Necessary for the TLR2-mediated inflammatory response and activation of NF-kappa-B: upon beta-glucan binding, recruits SYK via its ITAM motif and promotes a signaling cascade that activates some CARD domain-BCL10-MALT1 (CBM) signalosomes, leading to the activation of NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines . Enhances cytokine production in macrophages and dendritic cells . Mediates production of reactive oxygen species in the cell . Mediates phagocytosis of C.albicans conidia . Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cel...

Product :1mg/ml in PBS, pH 7.3, 50% glycerol, 0.05% BSA, and 0.05% Proclin300.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Dectin 1 protein

BiowMW :~27.4 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BGR; CLECSF12; DECTIN1; C-type lectin domain family 7 member A; Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1; DC-associated C-type lectin 1; Dectin-1

Immunogen :A synthetic peptide encompassing a sequence within mouse Dectin 1 protein.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of c-FER expression in HEK293T (A), HeLa (B), NIH3T3 (C) whole cell lysates.