Product Name :NPS polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Neuropeptide S: Ligand for NPSR1 . Binds to its receptor with nanomolar affinity and initiates a G(q)/GNAQ-dependent phospholipase C-activating signaling pathway. This results in Ca(2+) mobilization from intracellular stores and increased intracellular Ca(2+) levels . In addition to this pathway, NPS binding to its receptor activates cAMP/PKA signal transduction . Finally, both pathways converge to activate ERK1/ERK2 phosphorylation and signaling cascade . Modulates arousal and anxiety. May play an important anorexigenic role (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of NPS protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Neuropeptide S
Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human NPS.
Modification :Unmodification
